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Sea Grant seeks new drugs from the sea
Author
William FenicalAuthor Affiliations
W. Fenical is Director, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, UC San Diego.Publication Information
Hilgardia 51(4):45-49. DOI:10.3733/ca.v051n04p45. July 1997.
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Abstract
After more than 20 years of leadership in the field of marine drug discovery, Sea Grant researchers are now demonstrating that marine organisms are an excellent source of new drugs. New treatments have been discovered for arthritis and cancer, and novel molecular probes have been commercialized that allow studies of previously unknown cellular processes. Through patenting and licensing, UC has begun to receive significant royalties for these discoveries. As this field matures, it has become clear that the world's oceans contain an enormous wealth of medical information that will continue to contribute to the discovery of new cures for human disease.
Further reading
Faulkner DJ. Chemical riches from the oceans. Chem in Brit. 1995. 31:680-4.
Fenical W. Marine biodiversity and the medicine cabinet: The status of new drugs from marine organisms. Oceanography. 1996. 9(1):23-7.
Fenical W. Marine bacteria: Developing a new chemical resource. Chem Rev. 1993. 93:1673-83. doi:10.1021/cr00021a001 https://doi.org/doi:10.1021/cr00021a001
Hay ME, Fenical W. Chemical ecology and marine biodiversity: Insights and products from the sea. Oceanography. 1996. 9(1):10-20.
Potts BCM, Faulkner DJ, Jacobs RS. Phospholipase A2 inhibitors from marine organisms. J Nat Prod. 1992. 55:1701-17. doi:10.1021/np50090a001 https://doi.org/doi:10.1021/np50090a001 PubMed PMID: 1294693
Senderowicz AMJ, Kaur G, Sainz E, et al. Jasplakinolide: Inhibition of prostate carcinoma cell growth in vitro with disruption of the actin cytoskeleton. J Nat Cancer Inst. 1995. 87:46-51. doi:10.1093/jnci/87.1.46 https://doi.org/doi:10.1093/jnci/87.1.46 PubMed PMID: 7666463
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