Electrophoresis of tobacco mosaic virus

Takahashi, W; Rawlins, T

Electrophoresis of tobacco mosaic virus

Authors

William N. Takahashi
T. E. Rawlins

Authors Affiliations

William N. Takahashi was Graduate student in Plant Pathology; T. E. Rawlins was Assistant Professor of Plant Pathology and Assistant Plant Pathologist in the Experiment Station.

Publication Information

Hilgardia 4(15):441-463. DOI:10.3733/hilg.v04n15p441. April 1930.

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Abstract

Abstract does not appear. First page follows.

Introduction

Iwanowski’s⁽³⁴⁾ demonstration in 1892 that the mosaic disease of tobacco is caused by a filter-passing agent opened a new and extensive field of research in the pathology of both plants and animals. Since then a number of different virus4 diseases have been found affecting a variety of plants and animals. The bacteriophage has also been considered a virus by many workers.

Much literature dealing with various phases of virus diseases has been published. In the following review we have attempted to abstract only the work giving evidence as to the nature of the viruses.

Review of Literature

Cytological Studies.—For some time: pathologists resorted to cytological methods in their search for a visible parasite causing the virus diseases. A great deal of careful work has been done in this field. Iwanowski,⁽³⁵⁾ Dickson,⁽²¹⁾ McKinney, Eckerson and Webb,⁽⁴⁵⁾ Goldstein,⁽³⁰⁾ Palm,⁽⁵⁴⁾ Rawlins and Johnson,⁽⁵⁸⁾ Hoggan,⁽³²⁾ Kunkel,⁽³⁸⁾ Holmes,⁽³³⁾ Smith, ⁽⁶¹⁾ and various students of animal pathology have described abnormal intracellular bodies in virus-infected host tissues. The structure of these bodies is not sufficiently distinct to warrant the conclusion that they are a stage of a causal organism. In fact, many of the workers are inclined to the view that they are products of the causal agent or of the diseased host cell.

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