The immunization of fowls against chicken-pox (Epithelioma contagiosum), by subcutaneous injection of virus
AuthorJ. R. Beach
Author AffiliationsJ. R. Beach was Associate Professor of Veterinary Science and Associate Veterinarian in the Experiment Station.
Hilgardia 3(3):41-97. DOI:10.3733/hilg.v03n03p041. December 1927.
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The studies reported herein consist of a series of experiments in the immunization of fowls against chicken-pox (Epithelioma contagiosum) by the subcutaneous injection of vaccine containing the lesion tissue removed from fowls affected with the disease. The first report of a successful attempt to immunize fowls against chicken-pox by such means was that of Manteufel(1) in 1910. He reported success in immunizing fowls by injecting into the circulation or under the skin a lymph prepared from scraping of lesions on the comb or mucous membranes of the head of diseased birds mixed with physiologic salt solution and heated in a water bath at 55° C for one hour. According to this investigator, chickens treated in this manner were immune to infection for from one and one-half to two years even though there was no visible reaction following vaccination. Marked curative value for this preparation was also claimed.
 Manteufel. Beitrage zur Kenntnis der Immunitätserscheinungen bei den Sogenannten Geflügelpoken. Arbeit. Kaiserl. Gesundhtsamt. 1910. 33:305-312.
 Hadley F. B., Beach B. A. Controlling chicken-pox, sore-head, or contagious epithelioma by vaccination. Amer. Vet. Rev. 1913. 44:330-339.
 Mack W. B., Records E. The control of contagious epithelioma in chickens by vaccination. Nevada Agr. Exp. Sta. Bul. 1915. 82:1-16.
 Mack W. B., Records E. Contagious epithelioma in chickens. Its control by vaccination. Nevada Agr. Exp. Sta. Bul. 1916. 84:1-32. figs. 1-19
 Beach J. R. The diagnosis, therapeutics, and prophylaxis of chicken-pox (contagious epithelioma) of fowls. Jour. Amer. Vet. Med. Assn. 1920. 58:301-312.
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