Variation in the reactions obtained in repeated agglutination tests of the same fowls with Bacterium pullorum antigen
AuthorJ. R. Beach
Author AffiliationsJ. R. Beach was Assistant Professor of Veterinary Science and Associate Veterinarian in the Experiment Station.
Hilgardia 2(15):529-544. DOI:10.3733/hilg.v02n15p529. April 1927.
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The studies by Rettger and Rettger and Harvey, reported in four papers published between 1900 and 1909, definitely established the disease of young chicks commonly known as “white diarrhea” to be a specific infectious disease, the causative organism of which was designated Bacterium pullorum. Further studies by Rettger and his associates were reported in 1909, 1911 1912, and 1914. They determined that apparently healthy adult fowls may be carriers of Bact. pullorum. The infection in hens usually becomes localized in the ovaries and is eliminated in the eggs. When such eggs are used for hatching, the infection is transmitted to chicks. This is considered the usual source of Bact. pullorum infection in chicks. Jones(10), (11) in 1910 and 1911 and Gage in 1911 published the results of investigations which confirmed the findings of Rettger and his associates.
The most important problem in the prevention of the disease in chicks, therefore, became the detection and elimination of infected breeding stock. In 1913 Jones demonstrated that the agglutination test was of value for this purpose. His findings were confirmed by others and the testing of breeding flocks by this method has been practiced extensively for several years.
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